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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
Children's Oncology Group
Status
Recruiting
NCT ID
NCT01790152
This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer treatment. Studying samples of blood in the laboratory from patients receiving dexrazoxane hydrochloride may help doctors learn more about the effects of dexrazoxane hydrochloride on cells. It may also help doctors understand how well patients respond to treatment.
Intervention
Assessment of Therapy Complications, Laboratory Biomarker Analysis, Quality-of-Life Assessment, Questionnaire Administration
Condition
Hodgkin Lymphoma in Remission, Leukemia in Remission, Lymphoblastic Lymphoma, Osteosarcoma, Recurrent Leukemia, Recurrent Lymphoma, Recurrent Malignant Neoplasm
Investigators
Eric J Chow, Douglas J. Scothorn, Jennifer J. Greene Welch, Craig Lotterman, Steven J. Kuerbitz, Jennifer L. Reichek, Sharon B. Abish, Douglas S. Hawkins, Anne-Marie R. Langevin, Richard L. Tower, David L. Becton, Lillian R. Meacham, Narayana Gowda, Nina S. Kadan-Lottick, William D. Roberts, Rebecca E. McFall, Kenneth J. Cohen, Julienne Brackett, Madhu S. Gowda, Daniel C. Bowers, Nichole L. Bryant, Yvan Samson, Rene Y. McNall-Knapp, Emad K. Salman, Michael B. Harris, Jonathan D. Fish, Susan J. Lindemulder, Thomas B. Russell, Philip M. Monteleone, Janice F. Olson, Lynda M. Vrooman, Adonis N. Lorenzana, Eric C. Larsen, Laura E. Hogan, Bruno Michon, Wade T. Kyono, Douglas R. Strother, Jessica L. Heath, John F. Kuttesch, Saro H. Armenian, Judy L. Felgenhauer, Jason M. Fixler, Gregory E. Halligan, Angela R. Girvin, Marianne B. Phillips, Jacqueline M. Kraveka, Rajaram Nagarajan, Jaime M. Libes, Laura A. Campbell, Luis A. Clavell, Alan K. Ikeda, Jay Michael S. Balagtas, Dana A. Obzut, Alexandra M. Walsh, Ramamoorthy Nagasubramanian, Holly E. Pariury, Smita Bhatia, Anderson (Andy) B. Collier, Robert J. Hayashi, Site Public Contact
CT Research Area
Symptom Science

See list of participating sites