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Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers

Major Program

Cancer Prevention Clinical Trials Network

Research Group

Lung and Upper Aerodigestive Cancer

Status

Recruiting

NCT ID

NCT05121051

This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers. Broccoli seed and sprout extract may help break down and remove toxic substances caused by tobacco use and possibly produce substances that may protect cells from tobacco smoke-induced damage in current smokers.

Intervention

Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration, Questionnaire Administration

Condition

Cigarette Smoking-Related Carcinoma

Investigators

Julie E Bauman, Julie E. Bauman, Linda L. Garland, Mary E. Reid

CT Research Area

Prevention

See list of participating sites