Major Program
Supportive Care and Symptom Management
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
NRG Oncology
Status
Recruiting
NCT ID
NCT05646316
This phase III trial compares the effect of sentinel lymph node mapping to standard lymph node dissection in reducing the risk of swelling in the legs (lymphedema) in patients undergoing a hysterectomy for stage I endometrial cancer. Standard lymph node dissection removes lymph nodes around the uterus during a hysterectomy to look for spread of cancer from the uterus to nearby lymph nodes. Sentinel lymph node mapping uses a special dye and camera to look for cancer that may have spread to nearby lymph nodes. Comparing the results of the procedures may help doctors predict the risk of long-term swelling in the legs.
Intervention
Biospecimen Collection, Diagnostic Imaging Testing, Excisional Biopsy, Indocyanine Green Solution, Minimally Invasive Surgery, Pelvic Lymphadenectomy, Questionnaire Administration, Sentinel Lymph Node Mapping
Condition
Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Investigators
Edward J Tanner, Edward J. Tanner, Tara Castellano, Nicola M. Spirtos, Joan L. Walker, Matthew T. Oliver, Site Public Contact, Lisa M. Landrum, Kerry J. Rodabaugh, Jay W. Carlson, Robert T. Morris, Gautam G. Rao, Britt K. Erickson, Jayanthi S. Lea, Emily Hinchcliff, Abdulrahman Sinno, Sharad A. Ghamande
CT Research Area
Symptom Science