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Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma

Major Program
NCI Community Oncology Research Program
Research Group
Community Oncology and Prevention Trials
Sponsor
Eastern Cooperative Oncology Group
Status
Not yet recruiting
NCT ID
NCT07040280
The goal of this clinical trial is to compare the safety and effects of sulforaphane with the safety and effects of placebo on people's risk of developing melanoma. The main question it aims to answer is:

Will giving sulforaphane (a broccoli sprout extract) have a meaningful effect on how your atypical moles change over time? If there is an effect, will this lower your risk of developing melanoma?

Participants will:

Take sulforaphane or a placebo for 12 months Visit the clinic once every 3 months for checkups and tests You will keep a calendar which will help you keep track of when you take your tablets
Intervention
Derma-AI, Placebo, Sulforaphane (broccoli sprout extract)
Condition
Melanoma
Investigators
John Kirkwood, MD
CT Research Area
Prevention

See list of participating sites