Chemopreventive Agent Development

Designs, develops, implements, and monitors research on interventions that may block, reverse, or delay the early stages of cancer. Investigates nutrients, micronutrients, natural products, pharmacologic agents, biomolecules, and vaccines from preclinical to early-phase I clinical studies. Helps investigators to bridge the gaps between biology and identifying potential targets, and between discovery of targets and agents and clinical testing in people.

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Major Programs

Staff List

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Name, Email, Phone	Room	Group(s)/Office
Asefa, Wosene wosene.asefa@nih.gov 240-276-6422	5E504	Program Support Assistant \| Chemopreventive Agent Development
Biswas, Kajal, Ph.D. kajal.biswas2@nih.gov 240-276-5614	5E540	Program Officer \| Chemopreventive Agent Development
Boring, Daniel, R.Ph., Ph.D. [C] daniel.boring@nih.gov 240-276-6422		Contractor \| Chemopreventive Agent Development
Cholewa, Brian, Ph.D. brian.cholewa@nih.gov 240-276-7545	5E542	Deputy Chief \| Chemopreventive Agent Development
Clifford, John, Ph.D. john.clifford@nih.gov 202-235-4482	5E538	Program Officer \| Chemopreventive Agent Development
Gunasekharan, Vignesh, Ph.D. vignesh.gunasekharan@nih.gov 240-276-5814	5E536	Program Officer \| Chemopreventive Agent Development
Mohammed, Altaf, Ph.D. altaf.mohammed@nih.gov 240-276-6082	5E602	Program Officer \| Chemopreventive Agent Development
Nalli, Ancy, Ph.D., M.S. ancy.nalli@nih.gov 202-276-5265	5E570	Program Officer \| Chemopreventive Agent Development
Sei, Shizuko, M.D. shizuko.sei@nih.gov 240-276-5005	5E452	Co-Chief \| Chemopreventive Agent Development
Shoemaker, Robert, Ph.D. robert.shoemaker@nih.gov 240-276-7077	5E454	Co-Chief \| Chemopreventive Agent Development Acting Chief \| Nutritional Science
Vlad, Anda, M.D., Ph.D. anda.vlad@nih.gov 240-276-6422	5E546	Program Officer \| Chemopreventive Agent Development

Grants

PI Name Sort descending	PI Organization	Title	Grant Number	Program Official
Muzumdar, Mandar Deepak	Yale University United States	Targeting pancreatic endocrine-exocrine signaling in cancer development with incretin mimetics	1R01CA296916-01
Nelson, Randy J.	West Virginia University United States	Mechanism Underlying Sleep Disruption by Mammary Tumors	5R21CA276027-02	Marjorie Perloff, M.D.
Panigrahy, Dipak	Beth Israel Deaconess Medical Center United States	Control of cancer cachexia via stimulation of resolution of inflammation	5R01CA276107-02	Marjorie Perloff, M.D.
Park, Youngkyu	Cold Spring Harbor Laboratory United States	Preclinical Models for Cancer Therapeutic Development	5R50CA211506-09	Marjorie Perloff, M.D.
Pena, Maria Marjorette	University Of South Carolina At Columbia United States	The Role of Early Life Exposure to Antibiotics on Risk of Early Onset Colorectal Cancer	1R21CA281729-01A1
Peters, Jeffrey M	Pennsylvania State University, The United States	Unique targeting of PPARβ/δ regulation for cancer prevention and therapy	5R01CA239256-05	Marjorie Perloff, M.D.
Pyter, Leah M	Ohio State University United States	Chemotherapy-induced circadian master clock disruptions and fatigue	3R01CA270372-03S1	Marjorie Perloff, M.D.
Robertson, Gavin P.	Pennsylvania State Univ Hershey Med Ctr United States	Targeting Aldehyde Dehydrogenase for Cancer Prevention	5R01CA241148-05
Sands, Stephen Alan	Sloan-Kettering Inst Can Research United States	Prospective international phase-III study to improve neurocognitive outcomes in young children with low-risk medulloblastoma (YCMB-LR)	5R01CA283045-02	Marjorie Perloff, M.D.
Shirwan, Haval	University Of Missouri-Columbia United States	Developing a novel agonist of CD137 for cancer immunoprevention	1UG3CA290305-01	Altaf Mohammed, Ph.D.
Sorror, Mohamed	Fred Hutchinson Cancer Center United States	Novel Intervention Approaches to Alleviate Allogeneic Transplant-Related Morbidity and Mortality	5R01CA227092-06	Marjorie Perloff, M.D.
Tennis, Meredith A	University Of Colorado Denver United States	Modeling lung squamous cell carcinoma premalignancy and prevention	1R01CA298925-01
Thangaraju, Muthusamy	Augusta University United States	Bacteria-derived xenobiotics in colon cancer prevention: Link to GPR109A and colonic ketogenesis	5R01CA275840-02
Valdimarsdottir, Heiddis	Icahn School Of Medicine At Mount Sinai United States	Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation	5R01CA260961-03	Marjorie Perloff, M.D.
Yaddanapudi, Kavitha	University Of Louisville United States	A Stem Cell Based Exosomal Vaccine for the Prevention of Cancer	5R21CA277314-02