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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Storz, Peter

Mayo Clinic Jacksonville
United States

Deiminated molecules as markers for developing pancreatic cancer - A1 5R21CA279916-02 Matthew Young, Ph.D.
Upshaw, Jenica

Beth Israel Deaconess Medical Center
United States

A randomized trial of cardioprotective strategies in newly diagnosed diffuse large B-cell lymphoma and pre-existing cardiomyopathy or prior anthracycline exposure 1R37CA300969-01 Eileen Dimond, R.N., M.S.
Valdimarsdottir, Heiddis

Icahn School Of Medicine At Mount Sinai
United States

Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation 5R01CA260961-04 Marjorie Perloff, M.D.
Veiseh, Omid

Rice University
United States

Bioengineered lymphatic regenerating platform for treatment of breast cancer related lymphedema 1R01HL179534-01 Goli Samimi, Ph.D., M.P.H.
Vijayvergia, Namrata

Research Inst Of Fox Chase Can Ctr
United States

Exploring the Neuroprotective Potential of CBD in Preventing Oxaliplatin-Induced Neuropathy: A Prospective Study 1R21CA292276-01A1 Rachel Altshuler, Ph.D.
Wang, Hsiao-Lan

University Of Alabama At Birmingham
United States

A Motion Exergaming Approach to Promote Self-Managing Fatigue and Pain after Head and Neck Cancer Treatment 5R01CA244947-06 Goli Samimi, Ph.D., M.P.H.
Webster, Nicholas J

Veterans Medical Research Fdn/San Diego
United States

The Effect of Time-Restricted Eating on the Efficiency of Chemo- and Hormonal-Therapy in Breast Cancer 5R21CA288777-02 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Winger, Joseph Giles

Duke University
United States

Engage: A Randomized Controlled Trial Testing the Efficacy of a Telehealth-Delivered Psychosocial Intervention to Decrease Symptom Interference in Patients with Advanced Cancer 5R01CA291768-02 Brennan Streck, Ph.D., RN, M.P.H.
Wright, Alexi A

Dana-Farber Cancer Inst
United States

Randomized trial of REVITALIZE: A telehealth intervention to reduce fatigue interference among adults with advanced ovarian cancer on PARP inhibitors 5R01CA289547-02 Goli Samimi, Ph.D., M.P.H.
Xu, Xiangxi Mike

University Of Miami School Of Medicine
United States

Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapy 5R01CA286527-02 Rachel Altshuler, Ph.D.
Yang, Qing

University Of Texas Med Br Galveston
United States

The role of acute excitation of sensory neurons in the development of paclitaxel-induced peripheral neuropathy 5R01CA273001-02 Rachel Altshuler, Ph.D.
Yu, Anthony Francis

Sloan-Kettering Inst Can Research
United States

Intensive Blood Pressure Control During Cardiotoxic Breast Cancer Treatment (PROTECT) Trial 5R37CA273923-03 Eileen Dimond, R.N., M.S.
Zheng, Qin

Johns Hopkins University
United States

Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging 1R01CA291906-01A1 Rachel Altshuler, Ph.D.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Nutrition Therapy in Improving Immune System in Patients With Bladder Cancer That Can Be Removed by Surgery Laboratory Biomarker Analysis, Nutritional Intervention, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration SWOG Cancer Research Network Active, not recruiting
Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients Megestrol Acetate, Olanzapine, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment Enhanced Usual Care, Pathways Laurie McLouth Recruiting
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer Endocrine therapy interruption ETOP IBCSG Partners Foundation Active, not recruiting
Prevention of Frailty With Fisetin and Exercise in Breast Cancer Survivors Biospecimen Collection, Educational Intervention, Exercise Intervention, Fisetin, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration Jonsson Comprehensive Cancer Center Recruiting
Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program Health Promotion and Education, Informational Intervention, Questionnaire Administration, Smoking Cessation Intervention Alliance for Clinical Trials in Oncology Recruiting
Relaxation for Women With Breast Cancer Undergoing Radiotherapy Questionnaires, Relaxation Program, Saliva Testing M.D. Anderson Cancer Center Active, not recruiting
Reproductive Health Program in Patients With Cancer Standard practice related to reproductive heath, Training modules, algorithm, referral development ECOG-ACRIN Cancer Research Group Active, not recruiting
REVITALIZE: RCT to Reduce Fatigue in Adults With Ovarian Cancer on PARP Inhibitors Educational Materials, REVITALIZE Intervention Dana-Farber Cancer Institute Recruiting
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity Carvedilol, Laboratory Biomarker Analysis, Patient Observation SWOG Cancer Research Network Recruiting