| Title Sort descending | Intervention | Sponsor | Status |
|---|---|---|---|
| Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer | Biopsy, Biospecimen Collection, Bronchoscopy, Extended Release Metformin Hydrochloride, Questionnaire Administration | Northwestern University | Recruiting |
| Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia | Biopsy, Biospecimen Collection, Extended Release Metformin Hydrochloride, Placebo Administration | University of Arizona | Active, not recruiting |
| Obeticholic Acid for Prevention in Barrett's Esophagus | Biospecimen Collection, Esophageal Biopsy, Esophagogastroduodenoscopy, Liver Ultrasonographic Elastography, Obeticholic Acid, Placebo Administration, Questionnaire Administration | National Cancer Institute (NCI) | Recruiting |
| Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial | Biopsy Procedure, Biospecimen Collection, Placebo Administration, Urolithin A Supplement | National Cancer Institute (NCI) | Recruiting |
| PROTECT Study, "PRObiotics to TrEat Anal preCancer Trial | EXE-346 Probiotic, Placebo, Usual Care High Resolution Anoscopy (HRA) | University of California, San Francisco | Not yet recruiting |
| Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program | Health Promotion and Education, Informational Intervention, Questionnaire Administration, Smoking Cessation Intervention | Alliance for Clinical Trials in Oncology | Recruiting |
| Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD Study | Biospecimen Collection, Lisinopril, Liver Ultrasonographic Elastography, Magnetic Resonance Elastography, Magnetic Resonance Imaging, Proton Density Fat Fraction, Questionnaire Administration | Northwestern University | Active, not recruiting |
| STEMVAC in Patients With Early Stage Triple Negative Breast Cancer | CD105/Yb-1/SOX2/CDH3/MDM2-polyepitope Plasmid DNA Vaccine, Sargramostim | University of Washington | Recruiting |
| Testing a Combination of Vaccines for Cancer Prevention in Lynch Syndrome | Adenovirus 5 CEA/MUC1/Brachyury Vaccine Tri-Ad5, Biopsy Procedure, Biospecimen Collection, Colonoscopy, Nogapendekin Alfa, Placebo Administration, Questionnaire Administration | National Cancer Institute (NCI) | Active, not recruiting |
| Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer | Educational Intervention, Genetic Testing, Internet-Based Intervention, Interview, Patient Navigation, Survey Administration, Telemedicine | Alliance for Clinical Trials in Oncology | Not yet recruiting |
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Updates regarding government operating status and resumption of normal operations can be found at opm.gov.