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Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Active Prevention Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201 Biopsy Procedure, Biospecimen Collection, Colonoscopy, Dordaviprone, Questionnaire Administration, Sigmoidoscopy National Cancer Institute (NCI) Recruiting
Testing for Safety and Immune Effects of PDS0101, an Anti-HPV Therapy, Among People Living With HIV PDS0101 Weill Medical College of Cornell University Not yet recruiting
Testing Obeticholic Acid for Familial Adenomatous Polyposis Biopsy Procedure, Biospecimen Collection, Gastrointestinal Endoscopy, Obeticholic Acid, Placebo Administration, Questionnaire Administration National Cancer Institute (NCI) Recruiting
Testing RG1-VLP Vaccine to Prevent HPV-related Cancers Biospecimen Collection, HPV16 RG1 VLP Vaccine, Questionnaire Administration, Recombinant Human Papillomavirus Nonavalent Vaccine National Cancer Institute (NCI) Recruiting
Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma Derma-AI, Placebo, Sulforaphane (broccoli sprout extract) Eastern Cooperative Oncology Group Not yet recruiting
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Placebo Administration, Questionnaire Administration National Cancer Institute (NCI) Recruiting
Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients Biopsy, Calcipotriene, Fluorouracil University of Arizona Active, not recruiting
Testing the SurVaxM Vaccine for Lung Cancer Prevention Biospecimen Collection, Montanide ISA 51 VG, Questionnaire Administration, SVN53-67/M57-KLH Peptide Vaccine, Sargramostim National Cancer Institute (NCI) Not yet recruiting
To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration, Sinecatechins ECOG-ACRIN Cancer Research Group Recruiting
Trial of Exercise Therapy in Familial Adenomatous Polyp (FAP) Endurance Exercise Therapy University of Michigan Rogel Cancer Center Not yet recruiting