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Government Funding Lapse

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Active Prevention Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy Aspirin, Omeprazole University of Michigan Rogel Cancer Center Recruiting
Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer Acolbifene Hydrochloride, Biospecimen Collection, Mammography, Questionnaire Administration, Random Periareolar Fine-Needle Aspiration, Tamoxifen National Cancer Institute (NCI) Recruiting
Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH) Biospecimen Collection, Questionnaires University of California, San Francisco Recruiting
Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions. Mucoadhesive fenretinide-releasing system (FMS) Ohio State University Recruiting
Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial Biopsy Procedure, Biospecimen Collection, Mammography, Questionnaire Administration, Tamoxifen National Cancer Institute (NCI) Recruiting
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps 5-year and 10 Year Surveillance Colonoscopy after Qualifying Colonoscopy NRG Oncology Recruiting
GCC Agonist Signal in the Small Intestine Biopsy, Biospecimen Collection, Esophagogastroduodenoscopy, Linaclotide, Plecanatide University of Wisconsin, Madison Active, not recruiting
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction Biospecimen Collection, Mammography, Omega-3-Acid Ethyl Esters, Questionnaire Administration, Random Periareolar Fine-Needle Aspiration, Tamoxifen National Cancer Institute (NCI) Recruiting
Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer Biopsy Procedure, Extended Release Metformin Hydrochloride, Megestrol Acetate, Questionnaire Administration Northwestern University Active, not recruiting
Metformin and Nightly Fasting in Women With Early Breast Cancer Biospecimen Collection, Extended Release Metformin Hydrochloride, Monitoring, Nutritional Assessment, Short-Term Fasting M.D. Anderson Cancer Center Recruiting