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Consortium for Imaging and Biomarkers (CIB)

The Consortium for Imaging and Biomarkers (CIB) seeks to improve cancer screening, early detection of aggressive cancer, assessment of cancer risk, and cancer diagnosis by integrating imaging strategies with biomarkers into complementary approaches.

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About the Consortium for Imaging and Biomarkers

The Consortium for Imaging and Biomarkers aims to integrate imaging strategies and biomarker methodologies into a singular complementary approach to cancer detection. Investigators Work in multi-disciplinary teams to perform collaborative studies, exchange information, share knowledge and leverage common resources.

Overdiagnosis (finding cancers that will never affect a person’s health) and false positives (test results that show cancer when none is there) present significant clinical problems in the prevention, detection and treatment of cancer. There is a need to more accurately identify early-stage aggressive cancers and distinguish lesions that are life threatening from those that are not.

The Consortium for imaging and Biomarkers Research Units develop, optimize, and clinically validate novel methods to:

  • Detect aggressive cancers at the earliest stages possible;
  • Reduce overdiagnosis;
  • Reduce false positive tests; and
  • Identify lethal cancers from non-lethal disease.

The goal of the Consortium for imaging and Biomarkers is to develop improved methods for the early detection of aggressive cancer by managing overdiagnosis, reducing false positives and identifying lethal cancers from non-lethal disease using strategies aimed at effective integration and validation of imaging and biomarkers.

Funding Opportunity

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Herman, James G.

University Of Pittsburgh At Pittsburgh
United States

Optimizing Ultrasensitive DNA methylation detection for lung cancer and other malignancies 5U2CCA271885-04 Wendy Wang, Ph.D., M.Sc.
Herrmann, Joerg

Mayo Clinic Rochester
United States

TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) Trial 5R01CA233610-06 Eileen Dimond, R.N., M.S.
Herrmann, Joerg

Mayo Clinic Rochester
United States

TrAstuzumab Cardiomyopathy Therapeutic Intervention with Carvedilol (TACTIC) Trial 5R01CA233610-06 Eileen Dimond, R.N., M.S.
Hilakivi-Clarke, Leena A.

University Of Minnesota
United States

Effect of maternal obesity on breast cancer among offspring: role of the gut microbiota 5R01CA276775-03 Amit Kumar, Ph.D.
Hill, Joshua Aiden

Fred Hutchinson Cancer Center
United States

Immunoglobulin Replacement Therapy and Infectious Complications After CD19-Targeted CAR-T-Cell Therapy 5R01CA276040-03 Nancy J. Emenaker, Ph.D., RDN, LD, FAND
Hitchins, Megan P

H. Lee Moffitt Cancer Ctr & Res Inst
United States

Discovery and verification of methylated circulating tumor DNA markers for the detection of colorectal cancer in subjects under 50 years of age 7R01CA252042-05 Matthew Young, Ph.D.
Hollingsworth, Michael A.

University Of Nebraska Medical Center
United States

Pancreatic Cancer Detection Consortium 5U01CA210240-09 Matthew Young, Ph.D.
Hoshida, Yujin

Ut Southwestern Medical Center
United States

Therapeutic modulation of a proteomic HCC risk signature with statins in patients with liver cirrhosis 4U01CA288375-03 Sidney Fu, M.D.
Houghton, A Mcgarry

Fred Hutchinson Cancer Center
United States

Tumor-specific autoantibodies for SCLC early detection 5R01CA243328-06 Guillermo Marquez, Ph.D.
Howitt, Brooke E

Stanford University
United States

Unraveling heterogeneity in endometrial cancer via integrated single cell genotype-phenotype mapping 1R37CA303960-01 Goli Samimi, Ph.D., M.P.H.
Hruska, Carrie B

Mayo Clinic Rochester
United States

Density MATTERS Clinical Trial 5R01CA239200-05 Claire Zhu, Ph.D.
Hsu, Li

Fred Hutchinson Cancer Center
United States

Statistical Methods for Precision Prevention 1R01CA297681-01 Claire Zhu, Ph.D.
Hu, Jim

Weill Medical Coll Of Cornell Univ
United States

Pelvic fascia spARing radical prostatectomy TrIAL (PARTIAL) 5R01CA259173-04 Marjorie Perloff, M.D.
Hu, Shuiying

Ohio State University
United States

Targeting neuronal transport to ameliorate vincristine neurotoxicity 5R01CA272254-03 Rachel Altshuler, Ph.D.
Hu, Jim

Weill Medical Coll Of Cornell Univ
United States

Pelvic fascia spARing radical prostatectomy TrIAL (PARTIAL) 5R01CA259173-04 Marjorie Perloff, M.D.

Program Contact(s)

Sudhir Srivastava, Ph.D., M.P.H.
Email: sudhir.srivastava@nih.gov

Guillermo Marquez, Ph.D.
Email: guillermo.marquez@nih.gov