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Supportive Care and Symptom Management

The Supportive Care and Symptom Management program supports studies on the prevention or treatment of acute and chronic symptoms and morbidities related to cancer and its treatment. This includes the impact on the quality of life of patients and their informal caregivers. The program also supports studies of patients and their caregivers at the end of life.

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About Supportive Care and Symptom Management

The program supports research in three areas: prevention or treatment of acute or chronic symptoms and morbidities related to cancer, its treatment and caregiving (symptom management research); effects on quality of life from cancer, its treatment and caregiving (quality of life research); and end-of-life psychosocial issues, caregiving and treatment strategies (end-of-life research).

Through the NCI Community Oncology Research Program (NCORP), clinical trials are underway to evaluate therapies to prevent or ameliorate a broad range of symptoms and/or toxicities associated with cancer its treatment and caregiving. Other studies funded separately are investigating a range of treatment effects on health-related quality of life and a variety of influences on the end-of-life cancer experience. 

Topic Areas include: Anorexia, Cachexia, Cardiotoxicity, Caregiver Issues, Cognitive Dysfunction, Distress/Anxiety/Depression, End of Life, Fatigue, Geriatrics, Hot Flashes, Lymphedema, Medication Adherence, Mucositis, Multiple Symptoms, Musculoskeletal Symptoms, Nausea, Neuropathy, Nutrition, Oral Complications, Other Supportive Care Issues, Pain, Palliative Care, Pediatrics/Adolescents/Young Adult, Physical Functioning, Quality of Life, Skin Toxicities, Sleep Disorders, and Urinary Complications.

Selected Topics

Resources

Funding Opportunities

No matching Funding Opportunities were found.

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Grantee Details

PI Name Sort descending PI Organization Title Grant Number Program Official
Wright, Alexi A

Dana-Farber Cancer Inst
United States

Randomized trial of REVITALIZE: A telehealth intervention to reduce fatigue interference among adults with advanced ovarian cancer on PARP inhibitors 5R01CA289547-02 Goli Samimi, Ph.D., M.P.H.
Xiao, Yi

University Of Tx Md Anderson Can Ctr
United States

Exploring new strategy for breast cancer immunoprevention by targeting histamine receptor H1 5R21CA286318-02 Anda Vlad, M.D., Ph.D.
Xu, Xiangxi Mike

University Of Miami School Of Medicine
United States

Countering microtubule stabilization within hair follicles in ovarian cancer chemotherapy 5R01CA286527-02 Rachel Altshuler, Ph.D.
Xu, Chunhui

Emory University
United States

High-throughput assessment of chemotherapy-induced cardiotoxicity in 3D human cardiomyocytes 1R21CA285254-01A1 Eileen Dimond, R.N., M.S.
Yang, Qing

University Of Texas Med Br Galveston
United States

The role of acute excitation of sensory neurons in the development of paclitaxel-induced peripheral neuropathy 5R01CA273001-02 Rachel Altshuler, Ph.D.
Yu, Anthony Francis

Sloan-Kettering Inst Can Research
United States

Intensive Blood Pressure Control During Cardiotoxic Breast Cancer Treatment (PROTECT) Trial 5R37CA273923-03 Eileen Dimond, R.N., M.S.
Zheng, Qin

Johns Hopkins University
United States

Determining the function of medium to large diameter sensory neurons in paclitaxel-induced pain via large-scale in vivo DRG imaging 1R01CA291906-01A1 Rachel Altshuler, Ph.D.
Zhu, Yong

Univ Of Arkansas For Med Scis
United States

Explore piRNAs as a novel group of biomarkers for ovarian cancer early detection 1R21CA277412-01A1 Christos Patriotis, Ph.D., M.Sc.

Clinical Trials

Status
Title Sort descending Intervention Sponsor Status
Testing the Application of Mepitel Film During Radiation Therapy to Reduce Radiation Related Redness and Peeling in Breast Cancer Patients Following Mastectomy Best Practice, Quality-of-Life Assessment, Questionnaire Administration, Wound Dressing Material Alliance for Clinical Trials in Oncology Active, not recruiting
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy Best Practice, Exercise Counseling, Exercise Intervention, Magnetic Resonance Imaging, Neuropathy Assessment, Questionnaire Administration University of Rochester NCORP Research Base Active, not recruiting
Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer Carboplatin, Comprehensive Geriatric Assessment, Pembrolizumab, Pemetrexed, Quality-of-Life Assessment, Questionnaire Administration Alliance for Clinical Trials in Oncology Active, not recruiting
The Effect of Yoga on Nerve Pain Caused by Chemotherapy (Chemotherapy-Induced Peripheral Neuropathy) Education control, Usual care, Yoga Dana-Farber Cancer Institute Recruiting
The MIND-BC Study: MIND Diet for Breast Cancer Cognition MIND Diet, Usual Diet H. Lee Moffitt Cancer Center and Research Institute Recruiting
To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration, Sinecatechins ECOG-ACRIN Cancer Research Group Recruiting
Treating Breast Cancer Patients Undergoing Trastuzumab Treatment With Carvedilol to Reduce Incidence of Heart Failure Carvedilol Mayo Clinic Active, not recruiting
Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer Chemotherapy, Functional Assessment, Questionnaire Administration SWOG Cancer Research Network Active, not recruiting
Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer Best Practice, Biospecimen Collection, Electronic Health Record Review, Survey Administration, Triptorelin Pamoate Children's Oncology Group Recruiting
Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices Non-Interventional Wake Forest University Health Sciences Enrolling by invitation